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Schizophrenia and genes. Un'attività per il CLIL di Scienze in inglese

red - Di seguito viene proposto un testo sulla schizofrenia e i geni che può essere utilizzato per un'attività nelle classi CLIL di Scienze in inglese.

Schizophrenia and genes

It has been long understood that schizophrenia runs in families. People who have a close relative with schizophrenia are more likely to develop the disorder than are people who have no relatives with the illness. A child whose parent has schizophrenia has about a 10 percent chance of developing schizophrenia themselves. A monozygotic (identical) twin of a person with schizophrenia has the highest risk — a 40 to 65 percent chance of developing the illness. People who have second-degree relatives (aunts, uncles, grandparents, or cousins) with the disease also develop schizophrenia more often than the general population. By comparison, the risk of schizophrenia in the general population is about 1 percent. 

Scientists are continuing to study and better understand the genetic factors related to schizophrenia. We inherit our genes from both parents. Scientists believe several genes are associated with an increased risk of schizophrenia, but that no gene causes the disease by itself. In fact, recent research has found that people with schizophrenia tend to have higher rates of rare genetic mutations. These genetic differences involve hundreds of different genes and probably disrupt brain development. In addition, factors such as prenatal difficulties like intrauterine starvation or viral infections, perinatal complications, and various nonspecific stressors, seem to influence the development of schizophrenia. However, it is not yet understood how the genetic predisposition is transmitted, and it cannot yet be accurately predicted whether a given person will or will not develop the disorder.


1) Can Schizophrenia be inherited? Can a single gene cause Schizophrenia?

2) What do people with depression lose and how can they be treated?

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